VTAMA cream may help you or your child with eczema achieve clearer skin, with itch relief reported by some patients in as early as 2 days in the pivotal studies.
In clinical studies, up to 46% of patients with eczema using VTAMA cream (374 out of 813) achieved clear or almost clear skin in just 8 weeks compared to 18% of patients using a cream with no active ingredient.*
*Patients also achieved a ≥2-grade improvement from baseline in vIGA-AD score in 8 weeks.
VTAMA cream may help rapidly relieve itch due to eczema. Itch relief as early as Day 2 was reported in the pivotal studies by some patients.
~82% of patients (594 out of 728) entered with or got to clear or almost clear skin with VTAMA cream at least once in a 48-week open-label study.
Patients who achieved completely clear skin while on VTAMA cream were able to stop treatment and, on average, maintained clear or almost clear skin for about 2.5 months.
VTAMA cream is safe:
And well tolerated:
The most common adverse reactions (incidence ≥1%) in patients with atopic dermatitis treated with VTAMA cream were upper respiratory tract infection, red raised bumps around the hair pores (folliculitis), lower respiratory tract infection, headache, asthma, vomiting, ear infection, pain in extremity, and stomach-area (abdominal) pain.
*Patients/caregivers assessed the presence and degree of burning/stinging and itching at the application sites and recorded tolerability scores from (0) none to (1) slight, (2) mild, (3) moderate, or (4) strong/severe.
†Do not use VTAMA cream in your eyes, mouth, or vagina.
Here’s how tapinarof (the active ingredient in VTAMA cream) supports healthy skin function:
There are receptors in your skin called Aryl hydrocarbon receptors (AhR for short), and they play an important role in regulating your skin. But when you have eczema, your skin’s natural barrier is weakened and there is increased inflammation in your skin. Tapinarof helps fix the weak areas by supporting AhR. The specific way in which VTAMA cream works in eczema is unknown.
Tapinarof acts to boost skin barrier proteins and works to keep them at normal levels, as seen in studies of skin outside of the body.
Skin barrier proteins are essential proteins for the correct formation and function of the skin barrier. They’re very important to the function of healthy skin, but are found to not work as well in eczema.
Tapinarof reduces the activity of cells in the skin that cause inflammation, as seen in studies of mice and skin outside of the body.
Tapinarof increases your antioxidant activity, which decreases oxidative stress in your skin, as demonstrated in skin studies outside of the body.
Gain access to a wealth of resources tailored to help you manage your eczema effectively and confidently.
VIP Updates Terms of UseIndications: VTAMA® (tapinarof) cream, 1% is an aryl hydrocarbon receptor agonist indicated for:
Adverse Events: In plaque psoriasis, the most common adverse reactions (incidence ≥1%) were: red raised bumps around the hair pores (folliculitis), pain or swelling in the nose and throat (nasopharyngitis), skin rash or irritation, including itching and redness, peeling, burning, or stinging (contact dermatitis), headache, itching (pruritus), and flu (influenza).
Adverse Events: In atopic dermatitis, the most common adverse reactions (incidence ≥1%) were: upper respiratory tract infection, red raised bumps around the hair pores (folliculitis), lower respiratory tract infection, headache, asthma, vomiting, ear infection, pain in extremity, and stomach-area (abdominal) pain.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please read the Prescribing and Patient Information for VTAMA cream and discuss it with your doctor.
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