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INDICATION: VTAMA® (tapinarof) cream, 1% is a prescription medicine used on the skin (topical) to treat plaque psoriasis in adults.

IMPORTANT SAFETY INFORMATION: Most Common Side Effects In people treated for plaque psoriasis, the most common side effects included: red raised bumps around the hair pores (folliculitis), pain or swelling in the nose and throat (nasopharyngitis), skin rash or irritation (including itching and redness, peeling, burning, or stinging), headache, and flu.

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FDA approved to treat adults with plaque psoriasis. See the results.
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Looking for relief?

With VTAMA, you may achieve significantly clearer skin

In the 12-week clinical studies, up to 40% of adult patients achieved clear or almost clear skin (compared to 6% on cream with no active ingredient).
Before and After
Why VTAMA

Before and After

Behind the Ear
Behind the Ear
Belly Button
Face
Scalp
Elbow
Arm
Leg
Torso

Age: 66    Gender: Male    Patient: 1006-001    Study: Phase 4, open-label Intertriginous Plaque Psoriasis (in the skin folds) study

Before and after images of plaque psoriasis (behind the ear)

Baseline

Before and after images of plaque psoriasis (behind the ear)

Week 1

Before and after images of plaque psoriasis (behind the ear)

Week 12

Age: 38    Gender: Male    Patient: 1006-008    Study: Phase 4, open-label Intertriginous Plaque Psoriasis (in the skin folds) study

Before and after images of plaque psoriasis (belly button)

Baseline

Before and after images of plaque psoriasis (belly button)

Week 4

Before and after images of plaque psoriasis (belly button)

Week 12

Age: 24    Gender: Male    Patient: 1006-02    Study: Phase 4, open-label Head and Neck Plaque Psoriasis study

Before and after images of plaque psoriasis (face)

Baseline

Before and after images of plaque psoriasis (face)

Week 4

Before and after images of plaque psoriasis (face)

Week 12

Age: 75    Gender: Female    Patient: 1007-02    Study: Phase 4, open-label Head and Neck Plaque Psoriasis study

Before and after images of plaque psoriasis (scalp)

Baseline

Before and after images of plaque psoriasis (scalp)

Week 1

Before and after images of plaque psoriasis (scalp)

Week 12

Age: 67   Gender: Male    Patient: 2030-001    Study: Pivotal study

Before and after images of plaque psoriasis (scalp)

Baseline

Before and after images of plaque psoriasis (scalp)

Week 4

Before and after images of plaque psoriasis (scalp)

Week 12

Age: 56    Gender: Female    Patient: 1017-010    Study: Pivotal study

Before and after images of plaque psoriasis on the arm

Baseline

Before and after images of plaque psoriasis on the arm

Week 4

Before and after images of plaque psoriasis on the arm

Week 12

Age: 67    Gender: Male    Patient: 2030-001    Study: Pivotal study

Before and after images of plaque psoriasis on the knee

Baseline

Before and after images of plaque psoriasis on the knee

Week 4

Before and after images of plaque psoriasis on the knee

Week 12

Age: 63    Gender: Male    Patient: 2014-011    Study: Pivotal study

Before and after images of plaque psoriasis on the abdomen

Baseline

Before and after images of plaque psoriasis on the abdomen

Week 4

Before and after images of plaque psoriasis on the abdomen

Week 12

Take a look at the results! These images show the progress of some patients after using VTAMA for 12 weeks.

Please note that these photos are representative of one area on individual patients treated with VTAMA during the clinical studies. Individual results may vary.

See how clearer skin is possible with once‑daily VTAMA

In the 12-week clinical studies, up to 40% of adult patients achieved clear or almost clear skin (compared to 6% on cream with no active ingredient).

12 week chart

In the 12-week clinical studies, 36% and 48% of patients achieved at least 75% clearer skin while using VTAMA (compared to 10% and 7% using cream with no active ingredient, respectively).

80%

Up to 80% of adult patients saw some level of improvement in their plaques within 12 weeks while using VTAMA (compared to 35% using a cream with no active ingredient).*
*Physician Global Assessment (PGA) score of ≥1-grade improvement from baseline at Week 12.

58% icon

58% of patients achieved clear or almost clear skin at least once, in a 40-week open-label study.†
†In an open-label study, both the patient and their doctor know which treatment is being used.

health icon

VTAMA was proven to be safe and well tolerated for long-term use, as studied up to 52 weeks.

In people treated for plaque psoriasis, the most common side effects included: red raised bumps around the hair pores (folliculitis), pain or swelling in the nose and throat (nasopharyngitis), skin rash or irritation (including itching and redness, peeling, burning, or stinging), headache, and flu.

Adult patients who achieved clear skin while using VTAMA stopped treatment

In a 40-week open-label, long-term study, 312 patients achieved clear skin at least once—and stopped using VTAMA.

Those who achieved clear skin maintained clearer skin for an average of ~4 months, before starting treatment with VTAMA once again.

Ask your doctor if VTAMA might be right for you.

The Science Behind Tapinarof

What's AhR?

Your skin has receptors called aryl hydrocarbon receptors (AhR for short). These receptors play an important role in regulating your skin.

Affected skin with plaque psoriasis

When you have plaque psoriasis, your skin's natural barrier is weakened and there is increased inflammation in your skin.

VTAMA's active ingredient

Tapinarof, the active ingredient in VTAMA, supports the weak areas in your skin by activating AhR.

The specific way in which VTAMA works in plaque psoriasis is unknown.



VTAMA (tapinarof) cream tube
Patient Experience

See what adult patients have to say about VTAMA.

Learn More

Patient Brochure

This brochure is your quick and concise guide to VTAMA. Inside, you will find helpful information like safety info, patient images, and all the ins and outs of once-daily VTAMA.

Download

IMPORTANT SAFETY INFORMATION

INDICATION: VTAMA® (tapinarof) cream, 1% is a prescription medicine used on the skin (topical) to treat plaque psoriasis in adults.

IMPORTANT SAFETY INFORMATION VTAMA cream is for use on the skin (topical use) only. Do not use VTAMA cream in your eyes, mouth, or vagina.

Most Common Side Effects In people treated for plaque psoriasis, the most common side effects included: red raised bumps around the hair pores (folliculitis), pain or swelling in the nose and throat (nasopharyngitis), skin rash or irritation (including itching and redness, peeling, burning, or stinging), headache, and flu.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the Prescribing and Patient Information for VTAMA cream and discuss it with your doctor.

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US-VTA-113006 07/26

INDICATION: VTAMA® (tapinarof) cream, 1% is a prescription medicine used on the skin (topical) to treat plaque psoriasis in adults.

IMPORTANT SAFETY INFORMATION

VTAMA cream is for use on the skin (topical use) only. Do not use VTAMA cream in your eyes, mouth, or vagina.

Most Common Side Effects

In people treated for plaque psoriasis, the most common side effects included: red raised bumps around the hair pores (folliculitis), pain or swelling in the nose and throat (nasopharyngitis), skin rash or irritation (including itching and redness, peeling, burning, or stinging), headache, and flu.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the Prescribing and Patient Information for VTAMA cream and discuss it with your doctor.

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VTAMA® (tapinarof) cream, 1% is
now approved to treat eczema (atopic dermatitis) in adults and children down to 2 years of age.

VTAMA® (tapinarof) cream, 1% is
now approved to treat eczema (atopic dermatitis) in adults and children down to 2 years of age.

No thanks, take me to the VTAMA cream website
for adults with plaque psoriasis

US-VTMA-2400316

VTAMA® (tapinarof) cream, 1% is
now approved to treat eczema (atopic dermatitis) in adults and children down to 2 years of age.

VTAMA® (tapinarof) cream, 1% is
now approved to treat eczema (atopic dermatitis) in adults and children down to 2 years of age.

No thanks, take me to the VTAMA
cream website for adults with plaque psoriasis

IMPORTANT SAFETY INFORMATION
Indications: VTAMA® (tapinarof) cream, 1% is an aryl hydrocarbon receptor agonist indicated for:

  • the topical treatment of plaque psoriasis in adults.
  • the topical treatment of atopic dermatitis in adults and pediatric patients 2 years of age and older.

Adverse Events: In plaque psoriasis, the most common adverse reactions (incidence ≥1%) were: red raised bumps around the hair pores (folliculitis), pain or swelling in the nose and throat (nasopharyngitis), skin rash or irritation, including itching and redness, peeling, burning, or stinging (contact dermatitis), headache, itching (pruritus), and flu (influenza).

Adverse Events: In atopic dermatitis, the most common adverse reactions (incidence ≥1%) were: upper respiratory tract infection, red raised bumps around the hair pores (folliculitis), lower respiratory tract infection, headache, asthma, vomiting, ear infection, pain in extremity, and stomach-area (abdominal) pain.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.